Tuesday, July 14, 2009

Here is a dna sequence?

here is a dna sequence Tacctcttcgctaatatc. suppose the second c in the original template mutates to t write down the predicted template dna sequence. if i am asked this question on a test i would basicly take out the c and replace it with t right ? like this Tacttcttcgctaatatc. what would be the affect on the protein ?

Here is a dna sequence?
Tac ctc ttc gct aat atc





to





Tac ttc ttc gct aat atc





Assuming these are codons following the AUG start codon and thus part of the sequence coding the protein, the likely result is a change in the amino acid the codon specifies.





CTC - Leucine


TTC - Phenylalanine





Phenylalanine is a much larger AA than leucine, and could change the way the protein folds, or disrupt its ability to bind a substrate or regulator.

garden

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